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In an inactivated vaccine, the pathogen is killed or modified in such a way that it is unable to replicate. It cannot cause disease and is, therefore, suitable for those with a compromised immune system.
The inactivation step usually involves heat, radiation, or chemicals to destroy the pathogen’s genetic material, which stops it from replicating.
Inactivated vaccines can trigger a strong immune reaction, but it is usually not as strong as the reaction that live attenuated vaccines can produce. Due to this, a person may need booster shots to ensure ongoing protection.
The COVID-19 vaccines that Sinovac, Sinopharm, and Bharat Biotech have developed are inactivated vaccines.
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https://www.medicalnewstoday.com/articles/covid-19-how-do-in...
"... In an inactivated vaccine, the pathogen is killed or modified in such a way that it is unable to replicate. It cannot cause disease and is, therefore, suitable for those with a compromised immune system.
The inactivation step usually involves heat, radiation, or chemicals to destroy the pathogen’s genetic material, which stops it from replicating.
Inactivated vaccines can trigger a strong immune reaction, but it is usually not as strong as the reaction that live attenuated vaccines can produce. Due to this, a person may need booster shots to ensure ongoing protection.
The COVID-19 vaccines that Sinovac, Sinopharm, and Bharat Biotech have developed are inactivated vaccines. ..."