Nodejs/js runtimes in general get a lot of development effort to make the runtimes fast from Google et al. It's the default web language so there's a ton of effort put into optimizing the runtime. Python on the other hand is mostly a hacker/data science language that interops well with c, so there's not much incentive to make the base runtime fast. The rare times a company cares about python interpreter speed, they've built their own runtime for python instead.